"Eight healthy babies were born in Britain," reports Phys.org, "with the help of an experimental technique that uses DNA from three people to help mothers avoid passing devastating rare diseases to their children, researchers reported Wednesday."

Mutations in mitochondrial DNA "can cause a range of diseases in children that can lead to muscle weakness, seizures, developmental delays, major organ failure and death," and in rare cases even pre-IVF testing can't clearly detect their presence. Researchers have been developing a technique that tries to avoid the problem by using the healthy mitochondria from a donor egg. They reported in 2023 that the first babies had been born using this method... Using this method means the embryo has DNA from three people — from the mother's egg, the father's sperm and the donor's mitochondria — and it required a 2016 U.K. law change to approve it. It is also allowed in Australia but not in many other countries, including the U.S. Experts at Britain's Newcastle University and Monash University in Australia reported in the New England Journal of Medicine Wednesday that they performed the new technique in fertilized embryos from 22 patients, which resulted in eight babies that appear to be free of mitochondrial diseases. One woman is still pregnant...

Robin Lovell-Badge [a stem cell and developmental genetics scientist at the Francis Crick Institute who was not involved in the research] said the amount of DNA from the donor is insignificant, noting that any resulting child would have no traits from the woman who donated the healthy mitochondria...

In the U.K., every couple seeking a baby born through donated mitochondria must be approved by the country's fertility regulator. As of this month, 35 patients have been authorized to undergo the technique. Critics have previously raised concerns, warning that it's impossible to know the impact these sorts of novel techniques might have on future generations... But in countries where the technique is allowed, advocates say it could provide a promising alternative for some families.

"Nearly 2 million people protected their privacy by deleting their DNA from 23andMe after it declared bankruptcy in March," writes a Washington Post technology columnist.

"Now it's back with the same person in charge — and I still don't trust it." As of this week, genetic data from the more than 10 million remaining 23andMe customers has been formally sold to an organization called TTAM Research Institute for $305 million. That nonprofit is run by the person who co-founded and ran 23andMe, Anne Wojcicki. In a recent email to customers, the new 23andMe said it "will be operating with the same employees and privacy protocols that have protected your data." Never mind that Wojcicki and her privacy protocols are what put your DNA at risk in the first place...

The company is legally obligated to maintain and honor 23andMe's existing privacy policies, user consents and data protection measures. And as part of a settlement with states, TTAM also agreed to provide annual privacy reports to state regulators and set up a privacy board. But it hasn't agreed to take the fundamental step of asking for permission to acquire existing customers' genetic information. And it's leaving the door open to selling people's genes to the highest bidder again in the future...

Existing 23andMe customers have the right to delete their data or opt out of TTAM's research. But the new company is not asking for opt-in permission before it takes ownership of customers' DNA... Why does that matter? Because people who handed over the DNA 15 years ago, often to learn about their genetic ancestry, never imagined it might be used in this way now. Asking for new permission might significantly shrink the size (and value) of 23andMe's DNA database — but it would be the right thing to do given the rocky history. Neil M. Richards [the Washington University professor who served as privacy ombudsman for the bankruptcy court], pointed out that about a third of 23andMe customers haven't logged in for at least three years, so they may have no idea what is going on. Some 23andMe users never even clicked "agree" on a legal agreement that allowed their data to be sold like this; the word "bankruptcy" wasn't added to the company's privacy policy until 2022. And then there is an unknown number of deceased users who most certainly can't consent, but whose DNA still has an impact on their living genetic relatives...

[S]everal states have argued that their existing genetic privacy laws don't allow 23andMe to receive the information without getting permission from every single person. Virginia has an ongoing lawsuit over the issue, and the California attorney general's office told me it "will continue to fight to protect and vindicate the rights" of consumers....
Two more points of concern:

• "There is nothing in 23andMe's bankruptcy agreement or privacy statement to prevent TTAM from selling or transferring DNA to some other organization in the future."

• The article also notes a 2023 data breach affecting 6.9 million users, arguing "They haven't shown they can keep your data safe... 23andMe's financial struggles could make it hard to run a robust cybersecurity program."

Historian Garrett M. Graff describes his upcoming book, The Devil Reached Toward the Sky: An Oral History of the Making and Unleashing of the Atomic Bomb. "I assembled an oral history of the Manhattan Project, the bombings of Hiroshima and Nagasaki and the end of World War II in the Pacific, told through the voices of around 500 participants and witnesses of the events — including luminaries like Albert Einstein and Oppenheimer and political figures like President Harry Truman."

It was 80 years ago this week that physicists and 150 other leaders in the atomic bomb program "gathered in the desert outside Alamogordo, New Mexico, for the world's first test of a nuclear explosion." In an except from his upcoming book, Graff publishes quotes from eyewitness: Brig. Gen. Leslie Groves: I had become a bit annoyed with Fermi when he suddenly offered to take wagers from his fellow scientists on whether or not the bomb would ignite the atmosphere, and if so, whether it would merely destroy New Mexico or destroy the world. He had also said that after all it wouldn't make any difference whether the bomb went off or not because it would still have been a well worthwhile scientific experiment. For if it did fail to go off, we would have proved that an atomic explosion was not possible. Afterward, I realized that his talk had served to smooth down the frayed nerves and ease the tension of the people at the base camp, and I have always thought that this was his conscious purpose. Certainly, he himself showed no signs of tension that I could see...

As the hour approached, we had to postpone the test — first for an hour and then later for 30 minutes more — so that the explosion was actually three- and one-half hours behind the original schedule... Our preparations were simple. Everyone was told to lie face down on the ground, with his feet toward the blast, to close his eyes and to cover his eyes with his hands as the countdown approached zero. As soon as they became aware of the flash they could turn over and sit or stand up, covering their eyes with the smoked glass with which each had been supplied... The quiet grew more intense. I, myself, was on the ground between Bush and Conant...

Edward Teller: We all were lying on the ground, supposedly with our backs turned to the explosion. But I had decided to disobey that instruction and instead looked straight at the bomb. I was wearing the welder's glasses that we had been given so that the light from the bomb would not damage our eyes. But because I wanted to face the explosion, I had decided to add some extra protection. I put on dark glasses under the welder's glasses, rubbed some ointment on my face to prevent sunburn from the radiation, and pulled on thick gloves to press the welding glasses to my face to prevent light from entering at the sides... We all listened anxiously as the broadcast of the final countdown started; but, for whatever reason, the transmission ended at minus five seconds...

Kenneth T. Bainbridge: My personal nightmare was knowing that if the bomb didn't go off or hang-fired, I, as head of the test, would have to go to the tower first and seek to find out what had gone wrong...

Brig. Gen. Thomas F. Farrell: Dr. Oppenheimer held on to a post to steady himself. For the last few seconds, he stared directly ahead.
A few examples of how they remembered the explosion:

• William L. Laurence: There rose from the bowels of the earth a light not of this world, the light of many suns in one.

• Kenneth T. Bainbridge: I felt the heat on the back of my neck, disturbingly warm.

• George B. Kistiakowsky: I am sure that at the end of the world — in the last millisecond of the earth's existence — the last man will see what we have just seen.

• Brig. Gen. Thomas F. Farrell: Oppenheimer's face relaxed into an expression of tremendous relief.

• J. Robert Oppenheimer: We knew the world would not be the same. A few people laughed, a few people cried.

• Norris Bradbury, physicist, Los Alamos Lab: Some people claim to have wondered at the time about the future of mankind. I didn't. We were at war, and the damned thing worked.

At Sotheby's Geek Week auction, the largest known Martian meteorite on Earth sold for a record-breaking $5.3 million. The Associated Press reports: The 54-pound (25-kilogram) rock named NWA 16788 was discovered in the Sahara Desert in Niger by a meteorite hunter in November 2023, after having been blown off the surface of Mars by a massive asteroid strike and traveling 140 million miles (225 million kilometers) to Earth, according to Sotheby's. The estimated sale price before the auction was $2 million to $4 million. The identity of the buyer was not immediately disclosed. The final bid was $4.3 million. Adding various fees and costs, the official sale price was about $5.3 million, making it the most valuable meteorite ever sold at auction, Sotheby's said.

The live bidding was slow, with the auctioneer trying to coax more offers and decreasing the minimum bid increases. [...] The bidding for the Mars meteorite began with two advance offers of $1.9 million and $2 million. The live bidding slowly proceeded with increases of $200,000 and $300,000 until $4 million, then continued with $100,000 increases until reaching $4.3 million. The red, brown and gray meteorite is about 70% larger than the next largest piece of Mars found on Earth and represents nearly 7% of all the Martian material currently on this planet, Sotheby's says. It measures nearly 15 inches by 11 inches by 6 inches (375 millimeters by 279 millimeters by 152 millimeters). It was also a rare find. There are only 400 Martian meteorites out of the more than 77,000 officially recognized meteorites found on Earth, the auction house says.

An anonymous reader quotes a report from Live Science: In a world first, scientists have demonstrated an enigmatic phenomenon in quantum computing that could pave the way for fault-tolerant machines that are far more powerful than any supercomputer. The process, called "magic state distillation," was first proposed 20 years ago, but its use in logical qubits has eluded scientists ever since. It has long been considered crucial for producing the high-quality resources, known as "magic states," needed to fulfill the full potential of quantum computers. [...] Now, however, scientists with QuEra say they have demonstrated magic state distillation in practice for the first time on logical qubits. They outlined their findings in a new study published July 14 in the journal Nature.

In the study, using the Gemini neutral-atom quantum computer, the scientists distilled five imperfect magic states into a single, cleaner magic state. They performed this separately on a Distance-3 and a Distance-5 logical qubit, demonstrating that it scales with the quality of the logical qubit. "A greater distance means better logical qubits. A Distance-2, for instance, means that you can detect an error but not correct it. Distance-3 means that you can detect and correct a single error. Distance-5 would mean that you can detect and correct up to two errors, and so on, and so on," [explained Yuval Boger, chief commercial officer at QuEra who was not personally involved in the research]. "So the greater the distance, the higher fidelity of the qubit is -- and we liken it to distilling crude oil into a jet fuel."

As a result of the distillation process, the fidelity of the final magic state exceeded that of any input. This proved that fault-tolerant magic state distillation worked in practice, the scientists said. This means that a quantum computer that uses both logical qubits and high-quality magic states to run non-Clifford gates is now possible. "We're seeing sort of a shift from a few years ago," Boger said. "The challenge was: can quantum computers be built at all? Then it was: can errors be detected and corrected? Us and Google and others have shown that, yes, that can be done. Now it's about: can we make these computers truly useful? And to make one computer truly useful, other than making them larger, you want them to be able to run programs that cannot be simulated on classical computers."

alternative_right shares a report from ScienceAlert: Around a Sun-like star just 1,300 light-years away, a family of planets has been seen in its earliest moments of conception. Astronomers analyzed the infrared flow of dust and detritus left over from the formation of a baby star called HOPS-315, finding tiny concentrations of hot minerals that will eventually form planetesimals -- the 'seeds' around which new planets will grow. It's a system that can tell us about the very first steps of planet formation, and may even contain clues about how our own Solar System formed. The findings have been published in the journal Nature.

Cancer death rates in the U.S. have fallen by approximately one-third since the 1990s when adjusted for age, according to data cited in a new analysis of global cancer trends. The decline represents a steady, year-over-year reduction that began in the early 1990s and continues across developed countries.

Prevention efforts have contributed substantially to the decline. Reduced smoking rates in wealthy nations prevented more than 3 million cancer deaths since 1975 in America alone. Britain's HPV vaccination program, launched in 2008 for teenage girls, produced a 90% reduction in cervical cancer rates among women in their 20s within 15 years. Treatment advances have transformed outcomes for specific cancers. Childhood leukemia, once virtually fatal, now has a five-year survival rate above 90%.

Researchers have identified inexpensive drugs with cancer-prevention properties, including aspirin, which cuts bowel cancer risk in half for patients with Lynch syndrome. Future progress faces obstacles, however, including high treatment costs and planned cuts to the National Cancer Institute under the Trump administration. China overtook America as the primary source of cancer research in 2025.

Airbus's Silicon Valley innovation center Acubed and Google spinout SandboxAQ have successfully tested a quantum-sensing navigation device as an alternative to GPS during 150 hours of flights across the continental United States. The toaster-sized MagNav device uses quantum physics to measure unique magnetic signatures in Earth's crust [non-paywalled, syndicated link], with an AI algorithm matching those signatures to exact locations.

The technology achieved Federal Aviation Administration requirements by pinpointing aircraft location within two nautical miles 100% of the time and within 550 meters 64% of the time. SandboxAQ CEO Jack Hidary called it "the first novel absolute navigation system to our knowledge in the last 50 years." The analog system cannot be jammed or spoofed like GPS, which faces increasing tampering in the Middle East and around Ukraine and Russia.

NIST: There's a new record holder for the most accurate clock in the world. Researchers at the National Institute of Standards and Technology (NIST) have improved their atomic clock based on a trapped aluminum ion. Part of the latest wave of optical atomic clocks, it can perform timekeeping with 19 decimal places of accuracy.

Optical clocks are typically evaluated on two levels -- accuracy (how close a clock comes to measuring the ideal "true" time, also known as systematic uncertainty) and stability (how efficiently a clock can measure time, related to statistical uncertainty). This new record in accuracy comes out of 20 years of continuous improvement of the aluminum ion clock. Beyond its world-best accuracy, 41% greater than the previous record, this new clock is also 2.6 times more stable than any other ion clock. Reaching these levels has meant carefully improving every aspect of the clock, from the laser to the trap and the vacuum chamber.

The team published its results in Physical Review Letters. "It's exciting to work on the most accurate clock ever," said Mason Marshall, NIST researcher and first author on the paper. "At NIST we get to carry out these long-term plans in precision measurement that can push the field of physics and our understanding of the world around us."

The LIGO-Virgo-KAGRA Collaboration has detected the most massive black hole merger to date, forming a final black hole around 225 times the Sun's mass. Caltech reports: Before now, the most massive black hole merger -- produced by an event that took place in 2021 called GW190521 -- had a total mass of 140 times that of the Sun. In the more recent GW231123 event, the 225-solar-mass black hole was created by the coalescence of black holes each approximately 100 and 140 times the mass of the Sun. In addition to their high masses, the black holes are also rapidly spinning.

"The black holes appear to be spinning very rapidly -- near the limit allowed by Einstein's theory of general relativity," explains Charlie Hoy of the University of Portsmouth and a member of the LVK. "That makes the signal difficult to model and interpret. It's an excellent case study for pushing forward the development of our theoretical tools." Researchers are continuing to refine their analysis and improve the models used to interpret such extreme events. "It will take years for the community to fully unravel this intricate signal pattern and all its implications," says Gregorio Carullo of the University of Birmingham and a member of the LVK. "Despite the most likely explanation remaining a black hole merger, more complex scenarios could be the key to deciphering its unexpected features. Exciting times ahead!"

Armagh Observatory is marking a very special meteorological milestone as the institute celebrates 230 years of continuous weather observation. From a report: The unbroken tradition of handwritten data makes it the longest sequence of continuous weather information gathered anywhere in the UK and Ireland. Events are being held at Armagh Observatory on Monday to mark the significant anniversary. Nowadays, most weather data is gathered only by automated weather stations, but not in Armagh, where the human touch remains.

The first handwritten recording was made on the evening of 14 July 1795, when a measurement of the temperature and air pressure was recorded on a graph at the observatory that sits above the city of Armagh. The measurement was repeated the next day and every subsequent day for the next 230 years.

A scientific paper featuring an AI-generated image of a rat with an oversized penis was retracted three days after publication, highlighting broader problems plaguing academic publishing as researchers struggle with an explosion of scientific literature. The paper appeared in Frontiers in Cell and Developmental Biology before widespread mockery forced its withdrawal.

Research studies indexed on Clarivate's Web of Science database increased 48% between 2015 and 2024, rising from 1.71 million to 2.53 million papers. Nobel laureate Venki Ramakrishnan called the publishing system "broken and unsustainable," while University of Exeter researcher Mark Hanson described scientists as "increasingly overwhelmed" by the volume of articles. The Royal Society plans to release a major review of scientific publishing disruptions at summer's end, with former government chief scientist Mark Walport citing incentives that favor quantity over quality as a fundamental problem.

Researchers have created the world's first mRNA-based vaccine against a deadly, antibiotic-resistant bacterium — and they did it using the platform developed for COVID-19 vaccines.

Medical Express publishes their announcement: The vaccine developed by the team from the Institute for Biological Research and Tel Aviv University is an mRNA-based vaccine delivered via lipid nanoparticles, similar to the COVID-19 vaccine. However, mRNA vaccines are typically effective against viruses like COVID-19 — not against bacteria like the plague... In 2023, the researchers developed a unique method for producing the bacterial protein within a human cell in a way that prompts the immune system to recognize it as a genuine bacterial protein and thus learn to defend against it.

The researchers from Tel Aviv University and the Institute for Biological Research proved, for the first time, that it is possible to develop an effective mRNA vaccine against bacteria. They chose Yersinia pestis, the bacterium that causes bubonic plague — a disease responsible for deadly pandemics throughout human history. In animal models, the researchers demonstrated that it is possible to effectively vaccinate against the disease with a single dose.
The team of researchers was led by Professor Dan Peer at Tel Aviv University, a global pioneer in mRNA drug development, who says the success of the current study now "paves the way for a whole world of mRNA-based vaccines against other deadly bacteria."

"Certain kinds of gut microbes absorb toxic Pfas 'forever chemicals' and help expel them from the body," reports the Guardian, citing a "new first-of-its-kind University of Cambridge research shows." The microbes were found to remove up to 75% of some Pfas from the gut of mice. Several of the study's authors plan to develop probiotic dietary supplements that boost levels of helpful microbes in the human gut, which would likely reduce Pfas levels...

Pfas are a class of about 15,000 compounds most frequently used to make products water-, stain- and grease-resistant. They have been linked to cancer, birth defects, decreased immunity, high cholesterol, kidney disease and a range of other serious health problems. They are dubbed "forever chemicals" because they do not naturally break down in the environment. The US Environmental Protection Agency has found no level of exposure to Pfos or Pfoa, two of the most common Pfas compounds, in drinking water is safe. They have a half-life in human blood of anywhere from two to five years, by most estimates. That means the body expels half the amount of the chemical that is in blood during that period. Depending on blood levels, it can take decades to fully expel Pfas naturally.

Though the findings represent the first time gut microbes have been found to remove Pfas, they have been found to alleviate the impacts of other contaminants, such as microplastics...

The microbes largely addressed "long-chain" Pfas, which are larger compounds and more dangerous than smaller "short chains" because they stay in the body longer.

An anonymous reader shared this report from Cosmos magazine about a plan to "pick up those faint signals from billions of years ago." Astronomers are planning to launch a tiny spacecraft to the far side of the Moon to listen out for "ancient whispers" in a quest to uncover the secrets of the early universe. The mission will focus on understanding the 'Cosmic Dawn', a period in the early stages of the universe after the Big Bang but before the first stars and galaxies appeared.

One of the difficulties in studying this period of the universe is that silence is essential. With all the electronics and interference in our atmosphere, Earth becomes too loud, making it unsuitable for this kind of research... The proposed mission will utilise the Moon as a giant shield, blocking out the noise from Earth, in order to observe these signals...

The mission, known as CosmoCube, is a joint study between the UK's University of Portsmouth, University of Cambridge and Rutherford Appleton Laboratory Space... CosmoCube's radio will operate at low frequencies (10-100MHz), which should hopefully be able to detect extremely faint signals. The team hope to reach lunar orbit before the end of the decade, with a roughly 5-year roadmap planned.
The article includes this quote from Professor David Bacon, from the University of Portsmouth and CosmoCube researcher. "It's incredible how far these radio waves have travelled, now arriving with news of the universe's history.

"The next step is to go to the quieter side of the Moon to hear that news."

It killed tens of millions of people in 14th century Europe," CNN reports, though "today, it's easily treated with antibiotics."

And yet "A resident of northern Arizona has died from pneumonic plague, health officials said Friday." Plague is rare to humans, with on average about seven cases reported annually in the U.S., most of them in the western states, according to federal health officials. The death in Coconino County, which includes Flagstaff, was the first recorded death from pneumonic plague since 2007, local officials said... The bubonic plague is the most common form of the bacterial infection, which spreads naturally among rodents like prairie dogs and rats. There are two other forms: septicemic plague that spreads through the whole body, and pneumonic plague that infects the lungs. Pneumonic plague is the most deadly and easiest to spread.

Major space industry players -- including SpaceX, Boeing, and Blue Origin -- are urging Congress to maintain funding for the TraCSS space traffic coordination program, warning that eliminating it would endanger satellite safety and potentially drive companies abroad. Under the proposed FY 2026 budget, the Office of Space Commerce's funding would be cut from $65 million to just $10 million. "That $55M cut is accomplished by eliminating the Traffic Coordination System for Space (TraCSS) program," reports The Register. From the report: "One of OSC's most important functions is to provide space traffic coordination support to US satellite operators, similar to the Federal Aviation Administration's role in air traffic control," stated letters from space companies including SpaceX, Boeing, Blue Origin, and others. The letters argue that safe space operations "in an increasingly congested space domain" are critical for modern services like broadband satellite internet and weather forecasting, but that's not all. "Likewise, a safe space operating environment is vital for continuity of national security space missions such as early warning of missile attacks on deployed US military forces," the letters added.

Industry trade groups sent the letters to the Democratic and Republican leadership of the House and Senate budget subcommittees for Commerce, Justice, Science, and Related Agencies, claiming to represent more than 450 US companies in the space, satellite, and defense sectors. The letters argue for the retention of the OSC's FY 2025 budget of $65 million, as well as keeping control of space traffic coordination within the purview of the Department of Commerce, under which the OSC is nested, and not the Department of Defense, where it was previously managed. "Successive administrations have recognized on a bipartisan basis that space traffic coordination is a global, commercial-facing function best managed by a civilian agency," the companies explained. "Keeping space traffic coordination within the Department of Commerce preserves military resources for core defense missions and prevents the conflation of space safety with military control."

In the budget request document, the government explained the Commerce Department was unable to complete "a government owned and operated public-facing database and traffic coordination system" in a timely manner. The private sector, meanwhile, "has proven they have the capability and the business model to provide civil operators" with the necessary space tracking data. But according to the OSC, TraCSS would have been ready for operations by January 2026, raising the question of why the government would kill the program so late in the game.

An anonymous reader quotes a report from Ars Technica: When Stanford University researchers asked ChatGPT whether it would be willing to work closely with someone who had schizophrenia, the AI assistant produced a negative response. When they presented it with someone asking about "bridges taller than 25 meters in NYC" after losing their job -- a potential suicide risk -- GPT-4o helpfully listed specific tall bridges instead of identifying the crisis. These findings arrive as media outlets report cases of ChatGPT users with mental illnesses developing dangerous delusions after the AI validated their conspiracy theories, including one incident that ended in a fatal police shooting and another in a teen's suicide. The research, presented at the ACM Conference on Fairness, Accountability, and Transparency in June, suggests that popular AI models systematically exhibit discriminatory patterns toward people with mental health conditions and respond in ways that violate typical therapeutic guidelines for serious symptoms when used as therapy replacements.

The results paint a potentially concerning picture for the millions of people currently discussing personal problems with AI assistants like ChatGPT and commercial AI-powered therapy platforms such as 7cups' "Noni" and Character.ai's "Therapist." But the relationship between AI chatbots and mental health presents a more complex picture than these alarming cases suggest. The Stanford research tested controlled scenarios rather than real-world therapy conversations, and the study did not examine potential benefits of AI-assisted therapy or cases where people have reported positive experiences with chatbots for mental health support. In an earlier study, researchers from King's College and Harvard Medical School interviewed 19 participants who used generative AI chatbots for mental health and found reports of high engagement and positive impacts, including improved relationships and healing from trauma.

Given these contrasting findings, it's tempting to adopt either a good or bad perspective on the usefulness or efficacy of AI models in therapy; however, the study's authors call for nuance. Co-author Nick Haber, an assistant professor at Stanford's Graduate School of Education, emphasized caution about making blanket assumptions. "This isn't simply 'LLMs for therapy is bad,' but it's asking us to think critically about the role of LLMs in therapy," Haber told the Stanford Report, which publicizes the university's research. "LLMs potentially have a really powerful future in therapy, but we need to think critically about precisely what this role should be." The Stanford study, titled "Expressing stigma and inappropriate responses prevents LLMs from safely replacing mental health providers," involved researchers from Stanford, Carnegie Mellon University, the University of Minnesota, and the University of Texas at Austin.

Stanford researchers have developed a blood-based AI tool that calculates the biological age of individual organs to reveal early signs of aging-related disease. The Mercury News reports: The tool, unveiled in Nature Medicine Wednesday, was developed by a research team spearheaded by Tony Wyss-Coray. Wyss-Coray, a Stanford Medicine professor who has spent almost 15 years fixated on the study of aging, said that the tool could "change our approach to health care." Scouring a single draw of blood for thousands of proteins, the tool works by first comparing the levels of these proteins with their average levels at a given age. An artificial intelligence algorithm then uses these gaps to derive a "biological age" for each organ.

To test the accuracy of these "biological ages," the researchers processed data for 45,000 people from the UK Biobank, a database that has kept detailed health information from over half a million British citizens for the last 17 years. When they analyzed the data, the researchers found a clear trend for all 11 organs they studied; biologically older organs were significantly more likely to develop aging-related diseases than younger ones. For instance, those with older hearts were at much higher risk for atrial fibrillation or heart failure, while those with older lungs were much more likely to develop chronic obstructive pulmonary disease.

But the brain's biological age, Wyss-Coray said, was "particularly important in determining or predicting how long you're going to live." "If you have a very young brain, those people live the longest," he said. "If you have a very old brain, those people are going to die the soonest out of all the organs we looked at." Indeed, for a given chronological age, those with "extremely aged brains" -- the 7% whose brains scored the highest on biological age -- were over 12 times more likely to develop Alzheimer's disease over the next decade than those with "extremely youthful brains" -- the 7% whose brains inhabited the other end of the spectrum.

Wyss-Coray's team also found several factors -- smoking, alcohol, poverty, insomnia and processed meat consumption -- were directly correlated with biologically aged organs. Poultry consumption, vigorous exercise, and oily fish consumption were among the factors correlated with biologically youthful organs. Supplements like glucosamine and estrogen replacements also seemed to have "protective effects," Wyss-Coray said. [...] The test ... would cost $200 once it could be operated at scale.

The U.S. government has canceled a proposed $900 million project to study in unprecedented detail the afterglow of the Big Bang, the cosmic microwave background (CMB) radiation. Science magazine: Known as CMB-S4, the project envisioned new arrays of ultrasensitive microwave telescopes at the South Pole and in Chile's Atacama Desert. Their goal: to detect patterns in the ancient light that would prove the newborn universe expanded in an exponential growth spurt called cosmic inflation.

The project, which could have delivered smoking gun evidence for a key theory in cosmology, was supposed to be a joint venture between the National Science Foundation (NSF) and the Department of Energy (DOE). However, yesterday, the agencies sent an unsigned statement to the leaders of the collaboration saying the project is off. "DOE and NSF have jointly decided that they can no longer support the CMB-S4 Project," it reads.