Bruce66423 shares a report from Nature: The World Health Organization (WHO) has quietly shelved the second phase of its much-anticipated scientific investigation into the origins of the COVID-19 pandemic, citing ongoing challenges over attempts to conduct crucial studies in China, Nature has learned. Researchers say they are disappointed that the investigation isn't going ahead, because understanding how the coronavirus SARS-CoV-2 first infected people is important for preventing future outbreaks. But without access to China, there is little that the WHO can do to advance the studies, says Angela Rasmussen, a virologist at the University of Saskatchewan in Saskatoon, Canada. "Their hands are really tied." [...]

"There is no phase two," Maria Van Kerkhove, an epidemiologist at the WHO in Geneva, Switzerland, told Nature. The WHO planned for work to be done in phases, she said, but "that plan has changed." "The politics across the world of this really hampered progress on understanding the origins," she said. Researchers are undertaking some work to pin down a timeline of the virus's initial spread. This includes efforts to trap bats in regions bordering China in search of viruses closely related to SARS-CoV-2; experimental studies to help narrow down which animals are susceptible to the virus and could be hosts; and testing of archived wastewater and blood samples collected around the world in late 2019 and early 2020. But researchers say that too much time has passed to gather some of the data needed to pinpoint where the virus originated. "The ending of the investigation is not a surprise," adds Bruce66423. "But why 'quietly'?"

A new report (PDF) from the Data Science 4 Everyone coalition reveals that data literacy skills among fourth and eighth-grade students have declined significantly over the last decade even as these skills have become increasingly essential in our modern, data-driven society. Phys.Org reports: Based on data from the latest National Assessment of Educational Progress results, the report uncovered several trends that raise concerns about whether the nation's educational system is sufficiently preparing young people for a world reshaped by the rise of big data and artificial intelligence. Key findings include:

- The pandemic decline is part of a much longer-term trend. Between 2019 and 2022, scores in the data analysis, statistics, and probability section of the NAEP math exam fell by 10 points for eighth-graders and by four points for fourth-graders. Declining scores are part of a longer-term trend, with scores down 17 points for eighth-graders and down 10 points for fourth-graders over the last decade. That means today's eighth-graders have the data literacy of sixth-graders from a decade ago, and today's fourth-graders have the data literacy of third-graders from a decade ago.

- There are large racial gaps in scores. These gaps exist across all grade levels but are at times most dramatic in the middle and high school levels. For instance, fourth-grade Black students scored 28 points lower -- the equivalent of nearly three grade levels -- than their white peers in data analysis, statistics, and probability.

- Data-related instruction is in decline. Every state except Alabama reported a decline or stagnant trend in data-related instruction, with some states -- like Maryland and Iowa -- seeing double-digit drops. The national share of fourth-grade math teachers reporting "moderate" or "heavy" emphasis on data analysis dropped five percentage points between 2019 and 2022.

Russia's space agency will hold off returning three astronauts from the International Space Station as it works with NASA to investigate a coolant leak issue that impacted an uncrewed freighter spacecraft last weekend. The Register reports: The Progress MS-21 -- also known as the Progress 82 spacecraft -- arrived at the floating space lab in October 2022 carrying water and other supplies. After months of being docked to the station's Poisk module, the vehicle suddenly began spewing liquid coolant. On February 11, engineers at the Russian Mission Control Center detected a drop in pressure inside its coolant loop, but the station and the crew onboard are safe.

The Progress 82 spacecraft is currently being filled with trash and is scheduled to undock on February 17 and be disposed of over the Pacific Ocean. It began leaking coolant just as the Russian uncrewed Progress 83 cargo spacecraft successfully docked with the station's Zvezda service module. NASA and Roscosmos are now investigating the coolant glitch on Progress 82 as it's the second Soyuz incident of late after the Soyuz MS-22 began leaking in December. It's not clear what might have caused that malfunction, although one possibility that has been floated is that a micrometeoroid pierced an exterior radiator.

Yury Borisov, Roscosmos's director general, said cosmonauts Sergey Prokopyev and Dmitry Petelin, as well as NASA astronaut Frank Rubio, will have to remain onboard until March at the earliest while officials examine the coolant loop's depressurization, according to Reuters. Their space ferry had been due to launch on February 20 but that has been pushed back to March 10 at the earliest. "Officials are monitoring all International Space Station systems and are not tracking any other issues," NASA concluded.

An anonymous reader quotes a report from Ars Technica: On Friday, in a blog post not even promoted by the company's Twitter account or a news release, Blue Origin quietly said its "Blue Alchemist" program has been working on [using the dusty lunar surface to manufacture solar panels] for the last two years. The company, founded by Jeff Bezos, has made both solar cells and electricity transmission wires from simulated lunar soil -- a material that is chemically and mineralogically equivalent to lunar regolith. The engineering work is based on a process known as "molten regolith electrolysis," and Blue Origin has advanced the state of the art for solar cell manufacturing. In this process, a direct electric current is applied to the simulated regolith at a high temperature, above 1,600-degrees Celsius. Through this electrolysis process, iron, silicon, and aluminum can be extracted from the lunar regolith. Blue Origin says it has produced silicon to more than 99.999 percent purity through molten regolith electrolysis.

The key advance made by Blue Alchemist is that its engineers and scientists have taken the byproducts of this reaction -- and these materials alone -- to fabricate solar cells as well as the protective glass cover that would allow them to survive a decade or longer on the lunar surface. Blue Origin will attempt to market the technology to NASA for use by its Artemis program to return humans to the Moon in a "sustainable" way. NASA and its international partners seek to differentiate Artemis from the Apollo program by more extended stays on the Moon and building infrastructure such as power systems.

"Although our vision is technically ambitious, our technology is real now," the company said in its blog post. "Blue Origin's goal of producing solar power using only lunar resources is aligned with NASA's highest priority Moon-to-Mars infrastructure development objective." This is a notable research breakthrough, as the same electrolysis process could also be used to produce metals for building habitats and other structures, as well as oxygen. These are all important for "living off the land" if humans are to avoid the expense of needing to bring everything from Earth to live and work in space. While it is a long way from lab experiments to manufacturing on the Moon, these experiments are a critical first step.

"In the foothills of a Martian mountain, NASA's Curiosity rover found stunning new evidence of an ancient lake in the form of rocks etched with the ripples of waves," reports CNN.

But they add that the evidence "appeared in an unlikely place." The rover is traversing an area of Mars called the "sulfate-bearing unit" that researchers previously thought would only show evidence of mere trickles of water, as scientists believed the rocks there formed as the surface of the red planet was drying out. Instead, the rover found some of the clearest evidence yet of ancient waters.

"This is the best evidence of water and waves that we've seen in the entire mission," said Ashwin Vasavada, Curiosity's project scientist at NASA's Jet Propulsion Laboratory in Pasadena, California, in a statement. "We climbed through thousands of feet of lake deposits and never saw evidence like this — and now we found it in a place we expected to be dry...."

"Billions of years ago, waves on the surface of a shallow lake stirred up sediment at the lake bottom, over time creating rippled textures left in rock," according to a NASA news release.
From NASA's announcement: Having climbed nearly a half-mile above the mountain's base, Curiosity has found these rippled rock textures preserved in what's nicknamed the 'Marker Band' — a thin layer of dark rock that stands out from the rest of Mount Sharp....

Far ahead of the Marker Band, scientists can see another clue to the history of Mars' ancient water in a valley named Gediz Vallis. Wind carved the valley, but a channel running through it that starts higher up on Mount Sharp is thought to have been eroded by a small river.

NBC News reports: Eating fewer calories appears to slow the pace of aging and increase longevity in healthy adults, according to a study published Thursday in the journal Nature Aging.

The study, which was funded by the National Institute on Aging, part of the National Institutes of Health, is the first-ever randomized controlled trial that looked at the long-term impact of calorie restriction. It adds to an already large body of evidence that a calorie-restricted diet can provide substantial health benefits, including delayed aging, said the study's senior author, Dan Belsky, who is assistant professor of epidemiology at Columbia University's Mailman School of Public Health in New York City. "The main take-home of our study is that it is possible to slow the pace of biological aging and that it may be possible to achieve that slowing through modification of lifestyle and behavior," Belsky said.

In a phase 2 clinical trial, which ran for two years, 220 adults were randomized to cut their caloric intake by as much as 25% — 500 calories for people who generally consume 2,000 calories a day — or to make no changes to their diet. The participants had a body mass index, or BMI, ranging from 22 to 27.... Dr. Evan Hadley, director of the geriatrics and clinical gerontology division at the National Institute of Aging, said that most people in the calorie-restriction group only ended up cutting their daily caloric intake by about 12%. "But that 12% was enough to have significant changes," he said....

The researchers found that people who cut their calories slowed the pace of their aging by 2% to 3%, compared to people who were on a normal diet. That translates, Belsky said, to a 10% to 15% reduction in the likelihood of dying early. "We all have the power to change the trajectories of aging," he said.
Thanks to long-time Slashdot reader schwit1 for submitting the story.

A new pill could help alleviate constipation by delivering vibrations that "help kickstart the body's nature processes for getting rid of waste," reports Gizmodo. From the report: Vibrant still comes in the form of a pill, but before swallowing (around bedtime each night), it first needs to be activated by inserting it into a smartphone-connected pod. The pill makes its way through the body the same way food and other orally consumed medications do, but it isn't dissolved or broken down by stomach acids. Vibrant capsules are made from the same medical-grade material as pill cameras and are engineered to be durable enough to survive even accidental bites. Instead, it delivers relief by making small vibrations in three second intervals (three seconds on, three seconds off) to help stimulate nerve cells that trigger peristalsis: the wave like muscle contractions that push food and waste through the body.

After being swallowed, the pill vibrates for about two hours, goes dormant for around six hours, and then vibrates once again for another two hours. It remains completely intact until it exits the body (hopefully along with the blockage causing the constipation), when it's then flushed away. It doesn't sound like the motorized mechanism inside the pills is rechargeable -- not that you'd want to reuse one after its first fantastic voyage.

The pill's efficacy was tested in a study where 200 people dealing with chronic constipation took it every night for eight weeks, with 40% of the group reporting at least one additional bowel movement every week. Only 23% of an additional group of 149 people who took a placebo during the study reported having at least one more bowel movement per week. Unlike most laxatives, Vibrant doesn't cause side effects like diarrhea; however, a small minority of test subjects were actually able to feel the pill vibrating inside them. But it wasn't uncomfortable enough to stop them from taking it on a daily basis.

An anonymous reader quotes a report from MIT Technology Review: Imagine that you were provided no-cost fertility treatment and also offered a free DNA test to gauge which of those little IVF embryos floating in a dish stood the best chance of getting into a top college someday. Would you have the test performed? If you said yes, you're among about 40% percent of Americans who told pollsters they'd be more likely than not to test and pick IVF embryos for intellectual aptitude, despite hand-wringing by ethicists and gene scientists who think it's a bad idea. The opinion survey, published in the journal Science, was carried out by economists and other researchers who say surprisingly strong support for the embryo tests means the US might need to hurry up and set policies for the technology.

The new poll compared people's willingness to advance their children's prospects in three ways: using SAT prep courses, embryo tests, and gene editing on embryos. It found some support even for the most radical option, genetic modification of children, which is prohibited in the US and many other countries. About 28% of those polled said they'd probably do that if it was safe. The authors of the new poll are wrestling with the consequences of information that they helped discover via a series of ever larger studies to locate genetic causes of human social and cognitive traits, including sexual orientation and intelligence. That includes a report published last year on how the DNA differences among more than 3 million people related to how far they'd gone in school, a life result that is correlated with a person's intelligence.

The result of such research is a so-called "polygenic score," or a genetic test that can predict from genes whether -- among other things -- someone is going to be more or less likely to attend college. Of course, environmental factors matter plenty, and DNA is not destiny. Yet the gene tests are surprisingly predictive. In their poll, the researchers told people to assume that around 3% of kids will go to a top-100 college. By picking the one of 10 IVF embryos with the highest gene score, parents would increase that chance to 5% for their kid. It's tempting to dismiss the advantage gained as negligible, but "assuming they are right," Carmi says, it's actually "a very large relative increase" in the chance of going to such a school for the offspring in question -- about 67%. "The current poll found only 6% of people are morally opposed to IVF today, only about 17% have strong moral qualms about testing embryos, and 38% would probably do to boost education prospects if given the opportunity," adds the report.

A mini-planet orbiting in the frigid outer reaches of the solar system has a Saturn-like ring of dust and debris that defies the rules of physics, a new study has revealed. Space.com reports: The planet in question is called Quaoar and it's the seventh largest of the known dwarf planets of which Pluto is the king. Discovered in 2002 and about 697 miles wide (1,121 kilometers), Quaoar is one of the so-called trans-Neptunian objects, small planets orbiting beyond the solar system's outermost planet Neptune. Residing in the Kuiper Belt, the doughnut-shaped ring of rocky and icy debris in the outer solar system, Quaoar is a proud owner of its own moon, the 100-mile-wide (160 km) Weywot. And a recent observation campaign revealed that it also has a ring of material in its orbit. [...]

Quaoar's ring is at a very unusual distance from its parent body. In fact, before astronomers discovered Quaoar's ring in observations from several telescopes conducted between 2018 and 2021, they had thought that it was impossible for a ring to exist at such a distance. With a radius of about 2,420 miles (3,885 km) from Quaoar's center, the ring is too far away from the dwarf planet that its gravity should no longer be able to keep the material dispersed. Instead, it should coalesce under its own gravity and form another moon, just like Weywot. By not having done that, the ring has breached what astronomers call the Roche limit, the first known ring around a celestial body to have done so. [...] Now astronomers have to either rethink the Roche limit or come up with another explanation for the existence of Quaoar's ring. The study was published in the journal Nature.

An anonymous reader quotes a report from The Guardian: Scientists working on an experimental anti-ageing therapy claim to have broken a record by extending the lifespan of a lab rat called Sima. Named after the Hindi word for "limit" or "boundary", Sima is the last remaining survivor from a group of rodents that received infusions of blood plasma taken from young animals to see if the treatment prolonged their lives. Sima, who was born on February 28, 2019, has lived for 47 months, surpassing the 45.5 months believed to be the oldest age recorded in scientific literature for a female Sprague-Dawley rat, the researchers say. So far, Sima has outlived her closest rival in the study by nearly six months. "We have the oldest living female Sprague Dawley rat," said Dr Harold Katcher, a former biology professor at the University of Maryland, now chief scientific officer at Yuvan Research, a California-based startup.

Researchers have rushed to produce and trial therapies based on young blood plasma after numerous experiments found that infusions could reinvigorate aging organs and tissues. But while studies have found benefits for rodents, there is no evidence to date that the somewhat vampiric approach to youthfulness will help humans dodge the passage of time, despite the best wishes of Silicon Valley. The results from Katcher's latest study will be written up when Sima dies, but data gathered so far suggests that eight rats that received placebo infusions of saline lived for 34 to 38 months, while eight that received a purified and concentrated form of blood plasma, called E5, lived for 38 to 47 months. They also had improved grip strength. Rats normally live for two to three years, though a contender for the oldest ever is a brown rat that survived on a restricted calorie diet for 4.6 years.

A patent filing on the potential therapy describes how plasma from young mammals is purified and concentrated before use. Some components, such as platelets, are removed, as they can trigger immune reactions. The patent names pigs, cows, goats, sheep and humans as possible donors. The amount of plasma needed to produce a single concentrated dose is at least as much as the recipient has in their entire body, it states. If the therapy ever shows promise in humans -- large trials are needed in more animals first -- Katcher believes the plasma could be collected from pigs at abbatoirs.

SpaceX on Thursday test fired 31 of the 33 engines in the towering rocket booster of its Starship prototype, as the company prepares to launch the rocket to orbit for the first time. CNBC reports: Called a "static fire," the milestone test is the final major hurdle before SpaceX tries to launch the nearly 400-foot-tall rocket to space. The company said in a tweet shortly after the test that the engines at the base of the Super Heavy booster fired for "full duration," meaning the expected length of the test. CEO Elon Musk said in a subsequent tweet that SpaceX turned off one engine before the test and another engine "stopped itself." "Still enough engines to reach orbit!" Musk said.

SpaceX has steadily been building up to the first flight test of its Starship rocket. President and COO Gwynne Shotwell on Wednesday stressed the first launch attempt would be experimental. The company will next analyze the result of Thursday's static fire test. Shotwell estimated that a successful static would see SpaceX ready to launch the first Starship orbital flight "within the next month or so." You can watch the static fire test here.

Chip suppliers have warned that a European effort to impose a ban on "forever chemicals" will cause widespread disruption to already tight semiconductor supply chains. From a report: Five European countries, including Germany and the Netherlands, on Tuesday proposed that the EU phase out tens of thousands of so-called forever chemicals, known as PFAS, used in the production of semiconductors, batteries, aircraft, cars, medical equipment and even frying pans and ski wax.

The ban would constitute "the broadest restriction proposal in history," Frauke Averbeck, who led the proposal for the German Environment Agency, said. "It's a huge step for us to take." Richard Luit, senior policy adviser at the Dutch National Institute for Public Health and Environment, added: "If no action is taken we estimate that the societal costs will exceed the costs without a restriction." However, industry executives warned that a broad ban could have severe consequences for many sectors. Chemours, a leading supplier of high-end fluoropolymers, warned that the chemicals were "absolutely critical" for semiconductor manufacturing as well as a wide range of other industries.

Scientists have spotted 12 more moons around Jupiter, adding to an already-huge number that just seems to grow and grow. From a report: There's so many moons around this gas giant planet that astronomer Scott Sheppard struggles to keep track. "With this new haul, we're up to, I believe, 92 ... actually, I have to check that," he says, leaning over to type into his computer at the Carnegie Institution for Science, Earth and Planets Laboratory in Washington, DC. " Yeah, so 92 is the number that we have right now." His team is currently tracking some more moons that, once confirmed over the next year or two, should put Jupiter over 100.

There's good reason to keep looking for more moons, Sheppard says: If one was found in a convenient orbit, a spacecraft on a mission to Jupiter could fly close by and take a peek, letting scientists figure out what the moonlet is made of. That's important because Jupiter's small, outer moons are fairly mysterious. Astronomers suspect that they are remnants of the original building material that got used to form the solar system's biggest planet. Sheppard has been discovering new moons around Jupiter for over two decades, leading some colleagues to jokingly call him "Galileo," after the famous astronomer who first discovered that Jupiter had moons in 1610. Every few years, Sheppard and his fellow astronomers take advantage of better technology and bigger telescopes to add more moons to the tally. At the moment, Jupiter holds the record for the most known moons, beating out Saturn, which has 83.

In a study published Wednesday in PLOS Climate, a group of astrophysicists proposes shooting lunar dust into space to help partially shield sunlight to Earth. The Washington Post reports: The team used computer simulations to model various scenarios where massive quantities of dust (and we mean a lot of dust) in space can reduce the amount of Earthbound sunlight by 1 to 2 percent, or up to about six days of an obscured sun in a year. Their cheapest and most efficient idea is to launch dust from the moon, which would land into orbit between the sun and Earth and create a sunshade. Yes, the idea sounds like science fiction. Yes, it would require (a lot of) new engineering. Yes, there are more feasible climate mitigation tactics that can be employed now and in the near future. But the researchers view this rigorous physics experiment as a backup option that could aid -- not replace -- existing strategies to help humankind live on a more comfortable Earth. [...]

In the new study, the authors concede their idea isn't perfect but say it addresses some problems with previous concepts. For instance, the amount of material needed to actually shade the sun exceeds 10 billion kilograms (22 billion pounds), which is about 100 times more mass than humans have ever sent into space. Bromley says dust is very efficient at scattering sunlight relative to its size. The team considered different types of dust, scattering properties and size. The team found that aggregates of fluffy and highly porous particles scattered light the best, but they opted for a particle perhaps more easily accessible in space: moon dust. "We really do focus on lunar dust, just plain old, as-it-is lunar dust, without any indication of changing its shape," said Bromley, who said future moon mining could excavate the dust needed. Perhaps the greatest challenge is getting the right material exactly where you need it, Bromley said.

In one computer simulation, the team shot lunar dust from the moon's surface toward the sun. Bromley said the device to launch the lunar dust into space could be something similar to an electromagnetic gun, cannon or rocket -- picture a T-shirt cannon sending dust into orbit. In the simulation, the dust scattered along various routes until the team found suitable trajectories, which allowed the dust to concentrate temporarily and act as a sun shield. Bromley said the dust would periodically disperse away from Earth and throughout the solar system. In another simulation, the team shot off dust from a space platform about 1 million miles from Earth. This would be in an area known as L1 (Lagrange point 1), where objects tend to stay put because of equal gravitational pulls between the sun and Earth. This idea required more astronomical cost and effort because they would need a space platform and a dust supply that could be easily replenished. In either scenario, people on the ground wouldn't be able to see the shield or feel any difference, although some tools would probably be able to detect changes in the incoming solar radiation.

An anonymous reader quotes a report from Bloomberg: When Nestle SA's peanut allergy medicine first hit the market in 2020, Robert Wood, the director of pediatric allergy at Johns Hopkins Hospital in Baltimore, started preparing to offer it to the children he treats. But Covid-19 soon derailed in-person treatment, so over the next year and a half Wood and his colleagues told some 1,000 patients about the new drug instead, suggesting they consider it when the pandemic abated. Their responses came as a shock. Only six people were interested in a medicine that had been billed as a game changer for life-threatening allergies -- the first of its kind to be cleared by US authorities. Three years later, Wood has yet to prescribe the drug, Palforzia, and he isn't alone. Doctors and patients from California to Germany appear to be shunning the medicine in favor of the tried-and-true prescription for sufferers: simply avoiding peanuts and carrying an adrenaline injection for emergencies.

Nestle's chief executive officer, Mark Schneider, admitted as much in November, conceding that the drug's uptake had been slow. Schneider in 2020 bought out Palforzia's developer for $2.6 billion, paying a staggering 174% premium as he sought to take "the science business to the next level," snapping up vitamin makers such as Puritan's Pride and Solgar as well. The company is looking for a buyer, and the Swiss food giant says it will have to recognize a significant impairment to the deal's original value -- likely presaging a big writedown at a time when its core grocery business faces pressure from inflation. Maybe the company known for Nespresso capsules and Kit Kat chocolate wafers was never the right owner for a complex-to-administer niche medicine, but Schneider is on the hunt to find new avenues of growth in keeping with his strategic tilt toward health and wellness. The CEO "is looking to make acquisitions in new areas, and that inherently carries risks," says Martin Deboo, an analyst at Jefferies. "Palforzia is a signal of that." Nestle reiterated its commitment to nutritional health in an email and said Palforzia is safe and effective and solves the problem of variable potency that can hobble efficacy or trigger an allergic reaction with other less stringent treatments.

The product is essentially peanut protein that's been packed in a pill, standardized and categorized as a medicine after meeting the Food and Drug Administration's exacting clinical-trial requirements on safety and efficacy. By exposing children to tiny but gradually increasing amounts of the ingredient, Palforzia slowly raises their sensitivity threshold. But the process requires commitment by parents and kids to a demanding regime that lasts more than a year. [...] Palforzia is not without risk. During the clinical trials, about 9% of children suffered potentially dangerous immune reactions when their doses were being increased. [...] Bloomberg notes that Germany's Institute for Quality and Efficiency in Health Care concluded that Nestle's drug "doesn't offer any advantage over peanut avoidance." A UK panel that assess medicines' cost-effectiveness also found the drug to be quite expensive, costing about $6,220 per patient in England.

"As for Wood at Johns Hopkins, he says the allergy center would've lost money administering Palforzia -- something it was willing to do if there had been enough interest among patients. When asked whether some patients might've gone elsewhere for Palforzia, Wood says probably not."

"Man goes to the doctor for a sleep apnea diagnosis, a few months later he gets a letter from the state of Maryland about his sleep apnea -- and they won't tell him how they found out about it," writes Slashdot reader schwit1. NBC4 Washington reports: Dr. David Allick, a dentist in Rockville, was diagnosed with mild sleep apnea in June 2022. Months later, he received a letter from the MVA requesting additional information about his diagnosis in order "to determine your fitness to drive." The September 2022 letter noted failure to return the required forms, which included a report from his physician, could result in the suspension of his license. Allick said he isn't clear how the state learned about his medical diagnosis. But more importantly, he said he was previously unaware of a little-known Maryland law requiring people to report their sleep apnea diagnosis to state driving authorities. Allick said he still has questions about what prompted the ordeal. "Everybody I talked to -- nobody's heard of anything like this," he said, also acknowledging: "I'm sure they want to keep the roads safe." schwit1 adds: "How is this not a HIPAA violation?"

The investigation team at NBC4 Washington found that Allick is one of 1,310 people whose sleep apnea diagnoses "have led to medical reviews by the Maryland MVA." The state department didn't have data on how many of these Maryland drivers have had their license suspended.

Pollution from livestock farming, pharmaceuticals and healthcare is threatening to destroy a key pillar of modern medicine, as spills of manure and other pollution into waterways are adding to the global rise of superbugs, the UN has warned. From a report: Animal farming is one of the key sources of strains of bacteria that have developed resistance to all forms of antibiotics, through the overuse of the medicines in farming. Pharmaceutical pollution of waterways, from drug manufacturing plants, is also a major contributor, along with the failure to provide sanitation and control sewage around the world, and to tackle waste from healthcare facilities. Resistant superbugs can survive in untreated sewage.

The findings of the new report, published on Tuesday, show that pollution and a lack of sanitation in the developing world can no longer be regarded by the rich world as a faraway and localised problem for poor people. When superbugs emerge, they quickly spread, and threaten the health even of people in well-funded healthcare systems in the rich world. Poor sanitation and healthcare, and a lack of regulation in animal farming, create breeding grounds for resistant bacteria, and threaten global health as a result, the UN Environment Programme found in the report. As many as 10 million people a year could be dying by 2050 as a result of antimicrobial resistance (AMR), according to the UN, making it as big a killer as cancer is today. The rise of superbugs will also take an economic toll, resulting in the loss of about $3.4tn a year by the end of this decade, and pushing 24 million people into extreme poverty.

When shaken and chilled to minus 320 degrees Fahrenheit, ordinary frozen water "turns into something different," reports the New York Times, "a newly discovered form of ice made of a jumble of molecules with unique properties." The ice of our everyday lives consists of water molecules lined up in a hexagonal pattern, and those hexagonal lattices neatly stack on top of each other.... With permutations of temperature and pressure outside what generally occurs on Earth, water molecules can be pushed into other crystal structures.

"This is completely unexpected and very surprising," said Christoph Salzmann, a chemistry professor at University College London in England and an author of a paper published on Thursday in the journal Science that described the ice.... The new discovery shows, once again, that water, a molecule without which life is not known to be able to exist, is still hiding scientific surprises yet to be revealed. This experiment employed relatively simple, inexpensive equipment to reveal a form of ice that could exist elsewhere in the solar system and throughout the universe.
And according to LiveScience, the new form of ice has some unusual properties: Among them, Salzmann said, is that when the researchers compressed the medium-density ice and heated it to minus 185 F (minus 120 C), the ice recrystallized, releasing a large amount of heat. "With other forms of [amorphous] ice, if you compress them and you release the pressure, it's like nothing happened," Salzmann said. "But the MDA [medium-density amorphous ice] somehow has this ability to store the mechanical energy and release it through heating."

Medium-density amorphous ice might occur naturally on the ice moons of gas giant planets, Salzmann said, where the gravitational forces of the enormous worlds compress and shear the moons' ice. If so, the mechanical energy stored in this form of ice could influence the tectonics on these Hoth-like moons....

Scientists still debate the nature of water at extremely low temperatures. Any debate now needs to take into account medium-density amorphous ice, Salzmann said.
Thanks to long-time Slashdot reader fahrbot-bot for submitting the article.

Blobs of human brain tissue have been transplanted into the brains of rats in work that could pave the way for new treatments for devastating brain injuries. The Guardian reports: The groundbreaking study showed that the "human brain organoids" -- sesame seed-sized balls of neurons -- were able to integrate into the rat brain, linking up with their blood supplies and communicating with the rat neurons. The team behind the work suggest that eventually doctors might be able to grow blobs of brain tissue from a patient's own cells in the lab and use them to repair brain injuries caused by stroke or trauma.

Chen and colleagues grew human brain organoids in a dish until they were about 1.5mm in diameter. The balls of tissue were then transplanted into the brains of adult rats that had sustained injuries to their visual cortex. Within three months, the grafted organoids had integrated with their host's brain, hooking up with the blood supply, expanding to several times the initial volume and sending out projections that linked up with the rat's neurons, according to the study published in Cell Stem Cell. The scientists did not assess whether the implants improved how well the rats were able to function, but tests showed that the human neurons fired off electrical signals when the rats were exposed to flashing lights.