"What if ultrafast pulses of light could operate computers at speeds a million times faster than today's best processors?" asks the University of Arizona.

"A team of scientists, including researchers from the University of Arizona, are working to make that possible." In a groundbreaking international effort, researchers from the Department of Physics in the College of Science and the James C. Wyant College of Optical Sciences demonstrated a way to manipulate electrons in graphene using pulses of light that last less than a trillionth of a second. By leveraging a quantum effect known as tunneling, they recorded electrons bypassing a physical barrier almost instantaneously, a feat that redefines the potential limits of computer processing power. A study published in Nature Communications highlights how the technique could lead to processing speeds in the petahertz range — over 1,000 times faster than modern computer chips. Sending data at those speeds would revolutionize computing as we know it, said Mohammed Hassan, an associate professor of physics and optical sciences. Hassan has long pursued light-based computer technology and previously led efforts to develop the world's fastest electron microscope...

[T]he researchers used a laser that switches off and on at a rate of 638 attoseconds to create what Hassan called "the world's fastest petahertz quantum transistor... For reference, a single attosecond is one-quintillionth of a second," Hassan said. "That means that this achievement represents a big leap forward in the development of ultrafast computer technologies by realizing a petahertz-speed transistor." While some scientific advancements occur under strict conditions, including temperature and pressure, this new transistor performed in ambient conditions — opening the way to commercialization and use in everyday electronics. Hassan is working with Tech Launch Arizona, the office that works with investigators to commercialize inventions stemming from U of A research in order to patent and market innovations.

While the original invention used a specialized laser, the researchers are furthering development of a transistor compatible with commercially available equipment. "I hope we can collaborate with industry partners to realize this petahertz-speed transistor on a microchip," Hassan said.
Thanks to long-time Slashdot reader goslackware for sharing the news.

Rice plants can inherit tolerance to cold without changes to their genomes, according to a decade-long study carried out by researchers in China. From a report: The work, published in Cell this week, strengthens the evidence for a form of evolution in which environmental pressures induce heritable changes that do not alter an organism's DNA. The study conducted experiments that demonstrate, for the first time, the mechanism for these changes -- 'epigenetic' tweaks to chemical markers on the plant's DNA that don't actually tinker with the sequences themselves.

"What they're showing is extremely convincing; I would say that it's a landmark in the field," says Leandro Quadrana, a plant geneticist at the French National Centre for Scientific Research in Paris-Saclay. Michael Skinner, who studies epigenetic inheritance at Washington State University in Pullman, says the study adds to the growing body of evidence challenging the prevailing view of evolution that the only way that adaptations emerge is through gradual natural selection of randomly arising DNA mutations. This study shows that the environment isn't just a passive actor in evolution, but a selective force inducing a targeted change.

Harvard University's Galileo Project is using AI to automate the search for unidentified anomalous phenomena, marking a significant shift in how academics approach what was once considered fringe research. The project operates a Massachusetts observatory equipped with infrared cameras, acoustic sensors, and radio-frequency analyzers that continuously scan the sky for unusual objects.

Researchers Laura Domine and Richard Cloete are training machine learning algorithms to recognize all normal aerial phenomena -- planes, birds, drones, weather balloons -- so the system can flag genuine anomalies for human analysis. The team uses computer vision software called YOLO (You Only Look Once) and has generated hundreds of thousands of synthetic images to train their models, though the software currently identifies only 36% of aircraft captured by infrared cameras.

The Pentagon is pursuing parallel efforts through its All-domain Anomaly Resolution Office, which has examined over 1,800 UAP reports and identified 50 to 60 cases as "true anomalies" that government scientists cannot explain. AARO has developed its own sensor suite called Gremlin, using similar technology to Harvard's observatory. Both programs represent the growing legitimization of UAP research following 2017 Defense Department disclosures about military encounters with unexplained aerial phenomena.

Cornell University researchers have solved a kitchen mystery by demonstrating that sharp knives produce fewer and slower-moving droplets when cutting onions compared to dull blades. The findings used high-speed cameras and particle tracking to analyze droplet formation during onion cutting at speeds up to 20,000 frames per second.

The team discovered that onion droplets form through a two-stage process: an initial violent ejection driven by internal pressure, followed by slower fragmentation of liquid streams in air. Blunter blades create up to 40 times more droplets because the onion's tough outer skin acts as a barrier, allowing the softer interior tissue to compress significantly before rupturing and releasing pressurized liquid.

The research reveals that droplets are ejected at speeds between 1 and 40 meters per second, with the fastest ones posing the greatest risk of reaching a cook's eyes. Beyond tear reduction, the study suggests sharp knives may also limit the spread of foodborne pathogens, since atomized droplets can carry bacteria like Salmonella from contaminated cutting boards.

Astronomers have confirmed the existence of a bizarre planet in the Nu Octantis binary star system that orbits in reverse between two stars -- one of which is now a white dwarf. This retrograde orbit, once thought impossible, defies traditional planetary formation models and may have resulted from dramatic shifts in the system's history. New Scientist reports: The key observation was that the Nu Octantis planet is retrograde -- the planet and one star both orbit the second star, but they do so in opposite directions, with the planet having the tighter orbit around the second star. [Man Hoi Lee at the University of Hong Kong] says this is unusual but makes the system's configuration stable -- even though it means that the planet repeatedly moves through the narrow space between the two stars. His team was able to determine this with lots of certainty thanks to improved measuring devices, such as the HARPS spectrograph at the European Southern Observatory's 3.6-metre telescope in Chile. The fact that the planet's signal persisted through years of observation helped too. "We are pretty sure [the planet] is real, because if it was something like stellar activity, it shouldn't be so consistent in years of data," says Lee.

But this backwards-moving planet isn't the only exotic feature of Nu Octantis. The researchers used the European Southern Observatory's Very Large Telescope, also in Chile, to determine that one of its stars is a white dwarf, which means that it has reached the end of its life cycle, becoming denser and smaller. Lee says this complicates the Nu Octantis threesome's history because mathematical models of its past show that the planet's current orbit was impossible when this star was younger, bigger and brighter. So, the planet either used to orbit both stars at once, but then radically shifted trajectory when one of the two stars became a white dwarf, or it was formed from the mass that the star ejected as it transformed into a white dwarf. Future observations, and a lot more mathematical modelling, may be able to pinpoint which of these scenarios is more likely to have occurred, but both are rather novel, says Lee. The research has been published in the journal Nature.

An anonymous reader quotes a report from Phys.Org: Neuroscientists and materials scientists have created contact lenses that enable infrared vision in both humans and mice by converting infrared light into visible light. Unlike infrared night vision goggles, the contact lenses, described in the journal Cell, do not require a power source -- and they enable the wearer to perceive multiple infrared wavelengths. Because they're transparent, users can see both infrared and visible light simultaneously, though infrared vision was enhanced when participants had their eyes closed. [...] The contact lens technology uses nanoparticles that absorb infrared light and convert it into wavelengths that are visible to mammalian eyes (e.g., electromagnetic radiation in the 400-700 nm range). The nanoparticles specifically enable the detection of "near-infrared light," which is infrared light in the 800-1600 nm range, just beyond what humans can already see.

The team previously showed that these nanoparticles enable infrared vision in mice when injected into the retina, but they wanted to design a less invasive option. To create the contact lenses, the team combined the nanoparticles with flexible, nontoxic polymers that are used in standard soft contact lenses. After showing that the contact lenses were nontoxic, they tested their function in both humans and mice. They found that contact lens-wearing mice displayed behaviors suggesting that they could see infrared wavelengths. For example, when the mice were given the choice of a dark box and an infrared-illuminated box, contact-wearing mice chose the dark box whereas contact-less mice showed no preference. The mice also showed physiological signals of infrared vision: the pupils of contact-wearing mice constricted in the presence of infrared light, and brain imaging revealed that infrared light caused their visual processing centers to light up. In humans, the infrared contact lenses enabled participants to accurately detect flashing morse code-like signals and to perceive the direction of incoming infrared light.

An additional tweak to the contact lenses allows users to differentiate between different spectra of infrared light by engineering the nanoparticles to color-code different infrared wavelengths. For example, infrared wavelengths of 980 nm were converted to blue light, wavelengths of 808 nm were converted to green light, and wavelengths of 1,532 nm were converted to red light. In addition to enabling wearers to perceive more detail within the infrared spectrum, these color-coding nanoparticles could be modified to help color-blind people see wavelengths that they would otherwise be unable to detect. [...] Because the contact lenses have limited ability to capture fine details (due to their close proximity to the retina, which causes the converted light particles to scatter), the team also developed a wearable glass system using the same nanoparticle technology, which enabled participants to perceive higher-resolution infrared information. Currently, the contact lenses are only able to detect infrared radiation projected from an LED light source, but the researchers are working to increase the nanoparticles' sensitivity so that they can detect lower levels of infrared light.

Wisk Aero and NASA have signed a new five-year partnership to advance the safe integration of autonomous, all-electric aircraft into U.S. airspace, focusing on urban air mobility and regulated eVTOL flight. Electrek reports: Wisk Aero shared details of its refreshed partnership with NASA this week. The autonomous aviation specialist has signed a new five-year Non-Reimbursable Space Act Agreement (NRSAA) with the renowned space administration. Per Wisk, this new agreement focuses on critical research led by NASA's Air Traffic Management Exploration (ATM-X) project, which is centered around the advancement of commercialized autonomous aircraft travel under Instrument Flight Rules (IFR) in the National Airspace System (NAS).

As a specialist in autonomous, zero-emission aircraft, Wisk intends to continue its research alongside NASA to help regulators determine future eVTOL flight procedures and capabilities in the US. Regulatory developments on the to-do list for the latest NRSAA include optimizing airspace and route designs for highly automated UAM operations, establishing critical aircraft and ground-based safety system requirements for autonomous flight in urban environments, and establishing Air Traffic Control (ATC) communication protocols and procedures for seamless integration of future UAM aircraft. To achieve these goals, Wisk said its research with NASA will more specifically focus on utilizing advanced simulation and Live Virtual Constructive (LVC) flight environments, which combine live flights with a simulated airspace to enable researchers to assess future operations.

The teams from Wisk and NASA already met last month, continuing their research while beginning to determine how instrument flight procedures and advanced technologies can work together to enable safe autonomous passenger flights by 2030. Wisk Aero is a wholly owned subsidiary of Boeing based in California. The aerospace manufacturer said last year that it expects its pilotless air-taxi to begin carrying passengers "later in the decade."

Scientists have discovered a previously unknown bacterium aboard China's Tiangong space station. "It has been named Niallia tiangongensis, and it inhabited the cockpit controls on the station, living in microgravity conditions," reports Wired. From the report: According to China Central Television, the country's national broadcaster, taikonauts (Chinese astronauts) collected swab samples from the space station in May 2023, which were then frozen and sent back to Earth for study. The aim of this work was to investigate the behavior of microorganisms, gathered from a completely sealed environment with a human crew, during space travel, as part of the China Space Station Habitation Area Microbiome Program (CHAMP). A paper published in the Journal of Systematic and Evolutionary Microbiology describes how analysis of samples from the space station revealed this previously unseen bacterial species, which belongs to the genus Niallia. Genomic sequencing showed that its closest terrestrial relative is the bacterium Niallia circulans, although the Tiangong species has substantial genetic differences. [...]

It is unclear whether the newly discovered microbe evolved on the space station or whether it is part of the vast sea of as yet unidentified microorganisms on Earth. To date, tens of thousands of bacterial species have been cataloged, although there are estimated to be billions more unclassified species on Earth. The discovery of Niallia tiangongensis will provide a better understanding of the microscopic hazards that the next generation of space travelers will face and help design sanitation protocols for extended missions. It is still too early to determine whether the space bacterium poses any danger to taikonauts aboard Tiangong, although it is known that its terrestrial relative, Niallia circulans, can cause sepsis, especially in immunocompromised people.

Starfish Space plans to perform the first commercial satellite docking in orbit with its Otter Pup 2 mission, aiming to connect to an unprepared D-Orbit ION spacecraft using an electrostatic capture mechanism and autonomous navigation software. NASASpaceFlight.com reports: This follows the company's first attempt, which saw the Otter Pup 1 mission unable to dock with its target due to a thruster failure. The Otter Pup 2 spacecraft will be deployed from a quarter plate on the upper stage adapter of the SpaceX Falcon 9 rocket, placing it into a sun synchronous orbit altitude of 510 km inclined 97.4 degrees. The target will be a D-Orbit ION spacecraft which will simulate a client payload, which is not equipped with a traditional docking adapter or capture plate as you might see aboard a space station or other rendezvous target. Instead, Starfish Space's Nautilus capture mechanism will feature a special end effector connected to the end of the capture mechanism. This end effector will enable Otter Pup 2 to dock with the ION through electrostatic adhesion.

"An electromagnet will be integrated into the end effector and will be used as a backup option to the electrostatic end effector, to dock with the ION through magnetic attraction," the company notes. The goal is to eventually commission its Otter satellite servicing vehicle to allow for servicing of previously launched satellites. The company's first Otter missions include customers such as NASA, the U.S. Space Force, and Intelsat, with the goal of flying those missions as soon as 2026. [...] Following the thruster issues on the first mission, this flight will feature two ThrustMe thrusters, which use an electric propulsion system based on gridded ion thruster technology.

A new study reveals that about 3.8 million years after the solar system's first solids formed, Jupiter was twice its current size with a magnetic field 50 times stronger, profoundly influencing the structure of the early solar system. Phys.Org reports: [Konstantin Batygin, professor of planetary science at Caltech] and [Fred C. Adams, professor of physics and astronomy at the University of Michigan] approached this question by studying Jupiter's tiny moons Amalthea and Thebe, which orbit even closer to Jupiter than Io, the smallest and nearest of the planet's four large Galilean moons. Because Amalthea and Thebe have slightly tilted orbits, Batygin and Adams analyzed these small orbital discrepancies to calculate Jupiter's original size: approximately twice its current radius, with a predicted volume that is the equivalent of over 2,000 Earths. The researchers also determined that Jupiter's magnetic field at that time was approximately 50 times stronger than it is today.

Adams highlights the remarkable imprint the past has left on today's solar system: "It's astonishing that even after 4.5 billion years, enough clues remain to let us reconstruct Jupiter's physical state at the dawn of its existence." Importantly, these insights were achieved through independent constraints that bypass traditional uncertainties in planetary formation models -- which often rely on assumptions about gas opacity, accretion rate, or the mass of the heavy element core. Instead, the team focused on the orbital dynamics of Jupiter's moons and the conservation of the planet's angular momentum -- quantities that are directly measurable.

Their analysis establishes a clear snapshot of Jupiter at the moment the surrounding solar nebula evaporated, a pivotal transition point when the building materials for planet formation disappeared and the primordial architecture of the solar system was locked in. The results add crucial details to existing planet formation theories, which suggest that Jupiter and other giant planets around other stars formed via core accretion, a process by which a rocky and icy core rapidly gathers gas. The findings have been published in the journal Nature Astronomy.

An anonymous reader quotes a report from Ars Technica: There's a lot of matter around, which ensures that any antimatter produced experiences a very short lifespan. Studying antimatter, therefore, has been extremely difficult. But that's changed a bit in recent years, as CERN has set up a facility that produces and traps antimatter, allowing for extensive studies of its properties, including entire anti-atoms. Unfortunately, the hardware used to capture antiprotons also produces interference that limits the precision with which measurements can be made. So CERN decided that it might be good to determine how to move the antimatter away from where it's produced. Since it was tackling that problem anyway, CERN decided to make a shipping container for antimatter, allowing it to be put on a truck and potentially taken to labs throughout Europe. [...]

Overall, the hardware stayed cold, generally at a bit over 5 Kelvin. The exception was when the system was reconnected to the antimatter source hardware and the system reconnected to the electrical system at CERN. While those actions show up as temperature spikes, the superconducting magnets remained well under 7 Kelvin. An accelerometer was in place to track the forces experienced by the hardware while the truck was moving. This showed that changes in the truck's speed produced turbulence in the liquid helium, making measurements of its presence unreliable. Levels had dropped from about 75 percent of maximum to 30 percent by the time the system was reconnected, suggesting that liquid helium presents the key limiting factor in shipping. Measurements made while the system was in transit suggest that the whole process occurred losslessly, meaning that not a single proton escaped during the entire transport. The findings have been published in the journal Nature.

An anonymous reader shared this report from The Hill: A new study indicates the debilitating "brain fog" suffered by millions of long COVID patients is linked to changes in the brain, including inflammation and an impaired ability to rewire itself following COVID-19 infection. United Press International reported this week that the small-scale study, conducted by researchers at Corewell Health in Grand Rapids, Michigan, and Michigan State University, shows that altered levels of a pair of key brain chemicals could be the culprit.

The study marks the first time doctors have been able to provide scientific proof that validates the experiences of the approximately 12 million COVID "long-haulers" in the U.S. who have reported neurological symptoms. Researchers looked at biomarkers in study participants and found that those complaining of brain fog had higher levels of an anti-inflammatory protein that is crucial to regulating a person's immune system, UPI reported. They also showed lower serum levels of nerve growth factor, a protein vital to the brain's plasticity...

One of the biggest issues involving long COVID has been doctors' inability to find physical proof of the symptoms described by patients. The study has changed that, according to co-author Dr. Bengt Arnetz.

"Researchers are seeking a breakthrough in technologies to tackle PFAS contamination," reports the Washington Post — including experiments with ultraviolet light, plasma and sound waves: "We're in a good spot," said Christopher Higgins, a professor of civil and environmental engineering at the Colorado School of Mines who researches PFAS. "There's a lot of things being tested. ... Around the world, everyone is trying to work on this topic...." PFAS destruction technologies are beginning to show potential. Some methods have been licensed by companies that are rolling out the systems in real-world settings. "There's been a lot of research happening over the past few years looking at advanced destruction technologies, and there's been a lot of improvements and advancements, and we're now starting to see some of them actually at scale," said Anna Reade [a senior scientist and director of PFAS advocacy at the Natural Resources Defense Council].

An approach known as supercritical water oxidation is one of the more developed technologies, Reade and other experts said. It involves heating and pressurizing water to a specific point that creates the ideal conditions to break every carbon fluorine bond, said Amy Dindal [a PFAS expert with Battelle, a science and technology nonprofit that has developed a PFAS destruction technology]. The process used in a patented technology created by Battelle produces carbon dioxide and a form of fluorine that can be quickly neutralized to become a harmless salt. "It's a complete destruction and mineralization technology, because we're actually breaking all of the carbon fluorine bonds," Dindal said, adding that the technology is "PFAS agnostic...."

Another promising approach using heat and pressure was developed by researchers at the Colorado School of Mines [and already licensed by a company in Washington]. Known as hydrothermal alkaline treatment, or HALT, it involves adding a low-cost chemical reagent such as sodium hydroxide to superheated liquid water.... A destruction method that harnesses ultraviolet light has also emerged as a contender [has licensed by a company in Michigan]. When UV light oxidizes an electron-generating compound, it produces a powerful electron that's very reactive and strong enough to break carbon fluorine bonds... Other technologies are experimenting with the use of plasma, which can generate reactive electrons to break down PFAS but tends to require a large amount of energy. Researchers are also experimenting with a process that uses sound waves. High-intensity sound waves create small bubbles in a water system or liquid waste stream, Higgins said. As those bubbles collapse, they can generate the high temperatures and pressure needed to degrade PFAS.
But "At the end of the day, not using these chemicals unless it's absolutely necessary is the actually most effective tool in our toolbox," Reade said.

"With the help of more than five dozen fossils, paleontologists have uncovered a tiny three-eyed predator nicknamed the 'sea moth'," reports CNN, "that swam in Earth's oceans 506 million years ago."

Tiny as in 15 to 61 mm in total body length. (That's 0.60 to 2.4 inches...) But check out the illustration in CNN's article... Mosura fentoni, as the species is known, belongs to a group called radiodonts, an early offshoot of the arthropod evolutionary tree, according to a new study published Tuesday in the journal Royal Society Open Science. While radiodonts are now extinct, studying their fossilized remains can illuminate how modern arthropods such as insects, spiders and crabs evolved. One of the most diverse animal groups, arthropods are believed to account for more than 80% of living animal species, said lead study author Dr. Joe Moysiuk, curator of paleontology and geology at the Manitoba Museum in Winnipeg.

Well-preserved specimens of the previously unknown Mosura fentoni also reveal something that's never been seen in any other radiodont: an abdomen-like body region with 16 segments that include gills at its rear. This part of the creature's anatomy is similar to a batch of segments bearing respiratory organs at the rear of the body found in distant modern radiodont relatives like horseshoe crabs, woodlice and insects, Moysiuk said.... No animal living today quite looks like Mosura fentoni, Moysiuk said, although it had jointed claws similar to those of modern insects and crustaceans. But unlike those critters, which can have two or four additional eyes used to help maintain orientation, Mosura had a larger and more conspicuous third eye in the middle of its head.

"Although not closely related, Mosura probably swam in a similar way to a ray, undulating its multiple sets of swimming flaps up and down, like flying underwater," Moysiuk said in an email. "It also had a mouth shaped like a pencil sharpener and lined with rows of serrated plates, unlike any living animal." About the size of an adult human's index finger, Mosura and its swimming flaps vaguely resemble a moth, which led researchers to call it the "sea moth."
The Royal Society publication notes the etymology of the species name (Mosura fentoni is "from the name of the fictional Japanese monster, or kaiju... also known as 'Mothra'...in reference to the moth-like appearance of the animal."

Thanks to long-time Slashdot reader walterbyrd for sharing the news.

Australia's first orbital-class rocket launch was delayed after the nose cone of Gilmour Space's Eris rocket unexpectedly detached due to an electrical fault during final preparations. Although no damage occurred and no payload was onboard, the company is postponing the launch to investigate and replace the fairing before attempting another test flight. Ars Technica reports: Gilmour, the Australian startup that developed the Eris rocket, announced the setback in a post to the company's social media accounts Thursday. "During final launch preparations last night, an electrical fault triggered the system that opens the rocket's nose cone (the payload fairing)," Gilmour posted on LinkedIn. "This happened before any fuel was loaded into the vehicle. Most importantly, no one was injured, and early checks show no damage to the rocket or the launch pad."

Gilmour was gearing up for a launch attempt from a privately owned spaceport in the Australian state of Queensland early Friday, local time (Thursday in the United States). The company's Eris rocket, which was poised for its first test flight, stands about 82 feet (25 meters) tall with its payload fairing intact. It's designed to haul a payload of about 670 pounds (305 kilograms) to low-Earth orbit.

While Gilmour didn't release any photos of the accident, a company spokesperson confirmed to Ars that the payload fairing "deployed" after the unexpected electrical issue triggered the separation system. Payload fairings are like clamshells that enclose the satellites mounted to the top of their launch vehicle, protecting them from weather on the launch pad and from airflow as the rocket accelerates to supersonic speeds. Once in space, the rocket releases the payload shroud, usually in two halves. There were no satellites aboard the rocket as Gilmour prepared for its first test flight. The report notes that the Eris rocket is aiming to "become the first all-Australian launcher to reach orbit."

NASA engineers have successfully revived Voyager 1's backup thrusters, unused since 2004 and once considered defunct. Space.com reports: This remarkable feat became necessary because the spacecraft's primary thrusters, which control its orientation, have been degrading due to residue buildup. If its thrusters fail completely, Voyager 1 could lose its ability to point its antenna toward Earth, therefore cutting off communication with Earth after nearly 50 years of operation. To make matters more urgent, the team faced a strict deadline while trying to remedy the thruster situation. After May 4, the Earth-based antenna that sends commands to Voyager 1 -- and its twin, Voyager 2 -- was scheduled to go offline for months of upgrades. This would have made timely intervention impossible.

To solve the problem, NASA's team had to reactivate Voyager 1's long-dormant backup roll thrusters and then attempt to restart the heaters that keep them operational. If the star tracker drifted too far from its guide star during this process, the roll thrusters would automatically fire as a safety measure -- but if the heaters weren't back online by then, firing the thrusters could cause a dangerous pressure spike. So, the team had to precisely realign the star tracker before the thrusters engaged. Because Voyager is so incredibly distant, the team faced an agonizing 23-hour wait for the radio signal to travel all the way back to Earth. If the test had failed, Voyager might have already been in serious trouble. Then, on March 20, their patience was finally rewarded when Voyager responded perfectly to their commands. Within 20 minutes of receiving the signal, the team saw the thruster heaters' temperature soar -- a clear sign that the backup thrusters were firing as planned. "It was such a glorious moment. Team morale was very high that day," Todd Barber, the mission's propulsion lead at JPL, said in the statement. "These thrusters were considered dead. And that was a legitimate conclusion. It's just that one of our engineers had this insight that maybe there was this other possible cause, and it was fixable. It was yet another miracle save for Voyager."

An anonymous reader quotes a report from the Associated Press: U.S. health officials on Friday endorsed the first blood test that can help diagnose Alzheimer's and identify patients who may benefit from drugs that can modestly slow the memory-destroying disease. The test can aid doctors in determining whether a patient's memory problems are due to Alzheimer's or a number of other medical conditions that can cause cognitive difficulties. The Food and Drug Administration cleared it for patients 55 and older who are showing early signs of the disease.

The new test, from Fujirebio Diagnostics, Inc., identifies a sticky brain plaque, known as beta-amyloid, that is a key marker for Alzheimer's. Previously, the only FDA-approved methods for detecting amyloid were invasive tests of spinal fluid or expensive PET scans. The lower costs and convenience of a blood test could also help expand use of two new drugs, Leqembi and Kisunla, which have been shown to slightly slow the progression of Alzheimer's by clearing amyloid from the brain. Doctors are required to test patients for the plaque before prescribing the drugs, which require regular IV infusions. [...]

A number of specialty hospitals and laboratories have already developed their own in-house tests for amyloid in recent years. But those tests aren't reviewed by the FDA and generally aren't covered by insurance. Doctors have also had little data to judge which tests are reliable and accurate, leading to an unregulated marketplace that some have called a "wild west." Several larger diagnostic and drug companies are also developing their own tests for FDA approval, including Roche, Eli Lilly and C2N Diagnostics. The tests can only be ordered by a doctor and aren't intended for people who don't yet have any symptoms.

MIT has formally requested the withdrawal of a preprint paper on AI and scientific discovery due to serious concerns about the integrity and validity of its data and findings. It didn't provide specific details on what it believes is wrong with the paper. From a post: "Earlier this year, the COD conducted a confidential internal review based upon allegations it received regarding certain aspects of this paper. While student privacy laws and MIT policy prohibit the disclosure of the outcome of this review, we are writing to inform you that MIT has no confidence in the provenance, reliability or validity of the data and has no confidence in the veracity of the research contained in the paper. Based upon this finding, we also believe that the inclusion of this paper in arXiv may violate arXiv's Code of Conduct.

"Our understanding is that only authors of papers appearing on arXiv can submit withdrawal requests. We have directed the author to submit such a request, but to date, the author has not done so. Therefore, in an effort to clarify the research record, MIT respectfully request that the paper be marked as withdrawn from arXiv as soon as possible." Preprints, by definition, have not yet undergone peer review. MIT took this step in light of the publication's prominence in the research conversation and because it was a formal step it could take to mitigate the effects of misconduct. The author is no longer at MIT. [...]

"We are making this information public because we are concerned that, even in its non-published form, the paper is having an impact on discussions and projections about the effects of AI on science. Ensuring an accurate research record is important to MIT. We therefore would like to set the record straight and share our view that at this point the findings reported in this paper should not be relied on in academic or public discussions of these topics." The paper in question, titled "Artificial Intelligence, Scientific Discovery, and Product Innovation" and authored by Aidan Toner-Rodgers, investigated the effects of introducing an AI-driven materials discovery tool to 1,018 scientists in a U.S. R&D lab. The study reported that AI-assisted researchers discovered 44% more materials, filed 39% more patents, and achieved a 17% increase in product innovation. These gains were primarily attributed to AI automating 57% of idea-generation tasks, allowing top-performing scientists to focus on evaluating AI-generated suggestions effectively. However, the benefits were unevenly distributed; lower-performing scientists saw minimal improvements, and 82% of participants reported decreased job satisfaction due to reduced creativity and skill utilization.

The Wall Street Journal reported on MIT's statement.

Health authorities in densely-populated Hong Kong and Singapore have warned that Covid-19 cases are spiking, as a resurgent wave spreads through Asia. Bloomberg: The virus' activity in Hong Kong is now "quite high," Albert Au, head of the Communicable Disease Branch of the city's Center for Health Protection, told local media this week. The percentage of respiratory samples testing Covid-positive in Hong Kong recently reached its highest in a year.

Severe cases -- including deaths -- also reached its highest level in about a year to 31 in the week through May 3, the center's data shows. While the resurgence is yet to match the infection peaks seen in the past two years, rising viral load found in sewage water and Covid-related medical consultations and hospitalizations suggest the virus is actively spreading in the city of over 7 million people.

Rival financial hub Singapore is also on Covid alert. The city-state's health ministry released its first update on infection numbers in almost a year this month, as the estimated number of cases jumped 28% to 14,200 in the week through May 3 from the previous seven days while daily hospitalization rose around 30%. Singapore now only provides case updates when there is a noticeable spike.

MIT said Friday it can no longer stand behind a widely circulated paper on AI written by a doctoral student in its economics program. The paper said that the introduction of an AI tool in a materials-science lab led to gains in new discoveries, but had more ambiguous effects on the scientists who used it. WSJ: MIT didn't name the student in its statement Friday, but it did name the paper. That paper, by Aidan Toner-Rodgers, was covered by The Wall Street Journal and other media outlets. In a press release, MIT said it "has no confidence in the provenance, reliability or validity of the data and has no confidence in the veracity of the research contained in the paper."

The university said the author of the paper is no longer at MIT. The paper said that after an AI tool was implemented at a large materials-science lab, researchers discovered significantly more materials -- a result that suggested that, in certain settings, AI could substantially improve worker productivity. But it also showed that most of the productivity gains went to scientists who were already highly effective, and that overall the AI tool made scientists less happy about their work.